[et_pb_section fb_built=”1″ admin_label=”Section” _builder_version=”4.5.3″ _module_preset=”default”][et_pb_row _builder_version=”4.5.3″ _module_preset=”default”][et_pb_column type=”4_4″ _builder_version=”4.5.3″ _module_preset=”default”][et_pb_image src=”http:\/\/toxcel.com\/wp-content\/uploads\/2025\/07\/international-banner-scaled.jpg” alt=”UK and UN flag side by side” title_text=”international-banner” _builder_version=”4.5.3″ _module_preset=”default”][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.5.3″ _module_preset=”default”][et_pb_column type=”4_4″ _builder_version=”4.5.3″ _module_preset=”default”][et_pb_text _builder_version=”4.5.3″ _module_preset=”default” header_font=”Arial|600|||||||” header_text_color=”#00208a” header_font_size=”32px” custom_padding=”||21px|||”]<\/p>\n
[\/et_pb_text][et_pb_tabs active_tab_background_color=”#e5e5e5″ inactive_tab_background_color=”#35357f” active_tab_text_color=”#000000″ _builder_version=”4.5.3″ _module_preset=”default” tab_text_color=”#ffffff” body_font=”Arial||||||||” body_text_color=”#000000″ tab_font=”Arial||||||||” background_color=”#e5e5e5″ hover_enabled=”0″][et_pb_tab title=”EU and UK REACH Support” _builder_version=”4.5.3″ _module_preset=”default” hover_enabled=”0″]<\/p>\n
Achieving and maintaining compliance with the European Union\u2019s REACH (Registration, Evaluation,\u00a0Authorization\u00a0and Restriction\u00a0of Chemicals) regulation is essential for companies manufacturing or importing chemical substances into the EU or UK.\u00a0toXcel\u00a0<\/i><\/b>International helps clients successfully navigate REACH (EC 1907\/2006) and UK REACH requirements\u2014reducing regulatory risk,\u00a0expediting registration, and ensuring market access.\u00a0\u200b\u200b<\/p>\n
REACH compliance is required for substances manufactured or imported at quantities above 1\u00a0tonne\/ year. Testing requirements\u00a0increase with tonnage band and address the intrinsic physical\/ chemical, human and environmental toxicity properties of the\u00a0substance. A separate but similar system operates in the UK.\u00a0toXcel\u00a0International is available to help companies navigate the EU\u00a0and UK chemical substance regulations.\u00a0toXcel\u00a0can also help you with testing proposals and the placement, monitoring and\u00a0reporting of studies required by ECHA, and the evaluation of data for hazard classification.\u200b<\/p>\n
With a UK-based office and decades of global regulatory experience,\u00a0toXcel\u00a0provides practical, strategic support for REACHregistration and post-registration needs.\u200b<\/p>\n
Whether you’re preparing an initial registration or maintaining compliance, toXcel provides responsive, expert guidance tailored to\u00a0your product and business model.<\/p>\n
[\/et_pb_tab][et_pb_tab title=”European Cosmetics Regulation ” _builder_version=”4.5.3″ _module_preset=”default”]<\/p>\n
To legally place a cosmetic product on the EU market, companies must comply with the European Cosmetic <\/span>Products Regulation (EC) No. 1223\/2009, which mandates a Cosmetic Product Safety Report (CPSR) as a core <\/span>requirement. <\/span>toXcel International helps companies meet these obligations by preparing scientifically robust <\/span>CPSRs that ensure regulatory compliance and consumer safety.<\/span>\u200b<\/p>\n The<\/span> safety<\/span> of<\/span> a<\/span> cosmetic<\/span> is<\/span> assessed<\/span> based<\/span> on<\/span> the<\/span> known<\/span> properties<\/span> of<\/span> its <\/span>ingredients. <\/span>toXcel provides<\/span> literature-based<\/span> hazard<\/span> assessments<\/span> and<\/span> reviews<\/span> suppliers <\/span>specifications<\/span> and<\/span> data,<\/span> taking<\/span> into<\/span> account<\/span> any<\/span> impurities.<\/span> Our<\/span> overall<\/span> assessment<\/span> is <\/span>based on the properties of the product and anticipated human <\/span>exposure. The stability, microbial<\/span> quality,<\/span> packaging,<\/span> and<\/span> labelling<\/span> are<\/span> also<\/span> taken<\/span> into<\/span> consideration.<\/span> The<\/span> report must be signed by a suitably qualified person; <\/span>toXcel scientists include Registered Toxicologists<\/span> (DABT,<\/span> ERT)<\/span> and<\/span> Chartered<\/span> Biologists<\/span> (<\/span>CBiol<\/span>).<\/span> \u200b<\/p>\n With hundreds of successful CPSRs completed, <\/span>toXcel provides reliable, efficient support to help your <\/span>cosmetic products gain and maintain market access in the European Union.<\/span>\u200b<\/p>\n [\/et_pb_tab][et_pb_tab title=”CLP” _builder_version=”4.5.3″ _module_preset=”default”]<\/p>\n Proper classification and labeling of chemical substances and mixtures is essential for market access, user<\/span><\/span><\/span>safety, and regulatory compliance in the European Union (EU).\u00a0<\/span><\/span><\/span><\/p>\n Safety Data Sheets (SDS) in the EU must be based on a classification conforming to (EC) No 1272\/2008 on Classification, Labelling and Packaging of Substances and Mixtures (CLP Regulation) and the formatting and content must follow the description given in (EC) No\u00a01907\/2006 concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH).\u00a0CLP <\/span>implements the Globally <\/span>Harmonised<\/span> System (GHS) of <\/span>classification in the EU; similar legislation operates in the USA, Canada, Brazil, Australia and China. CLP requires <\/span>all importers, manufacturers and downstream users to classify, label and package substances and mixtures <\/span>adequately before they can be placed on the market. <\/span>\u200b<\/span><\/p>\n [\/et_pb_tab][et_pb_tab title=”Endocrine Disruptors in Europe ” _builder_version=”4.5.3″ _module_preset=”default”]<\/p>\n Endocrine-disrupting chemicals (EDCs) are increasingly prioritized under European Union (EU)\u00a0regulations due to their potential to interfere with hormonal systems and cause adverse health and\u00a0environmental effects. The EU is actively strengthening requirements under REACH and CLP to identify,\u00a0classify, and restrict substances with endocrine-disrupting properties.\u200b<\/p>\n toXcel\u00a0International is monitoring this evolving regulatory landscape and is ready to support companies\u00a0in meeting new compliance obligations and minimizing business risks.\u200b<\/p>\n Key regulatory updates include:\u200b<\/strong><\/p>\n \u200b<\/span><\/p>\n [\/et_pb_tab][et_pb_tab title=”Health Canada and PMRA ” _builder_version=”4.5.3″ _module_preset=”default”]<\/p>\n Successfully navigating Canadian pesticide regulations requires a deep understanding of the Pest Control <\/span>Products Act (PCPA) and Health Canada\u2019s Pest Management Regulatory Agency (PMRA) review process. <\/span>toXcel supports clients in preparing scientifically sound regulatory submissions to PMRA\u2014helping bring pesticide <\/span>products to the Canadian market efficiently and compliantly.<\/span>\u200b<\/p>\n PMRA only registers pesticide products that demonstrate both acceptable human health and environmental <\/span>risk profiles and proven value (efficacy) in their intended use. Unlike the US EPA, which generally only requires <\/span>efficacy data for public health pests, PMRA mandates value\/ efficacy data for all products. <\/span>A <\/span>registration<\/span> is<\/span> typically<\/span> granted<\/span> for<\/span> a<\/span> term<\/span> of<\/span> 5<\/span> years,<\/span> then<\/span> subject<\/span> to<\/span> renewal<\/span> (however,<\/span> a <\/span>registration<\/span> term<\/span> can<\/span> be<\/span> less<\/span> than<\/span> 5<\/span> years<\/span> if<\/span> it<\/span> is<\/span> determined<\/span> that<\/span> the<\/span> risks<\/span> or<\/span> value<\/span> should<\/span> be reviewed after a shorter period).<\/span> \u200b<\/p>\n While <\/span>toXcel cannot act as a Canadian agent, we have partners available in-country to act as agent for <\/span>submissions or <\/span>toXcel can prepare submission documentation and the PRZ electronic submission files for <\/span>clients with a legal presence in Canada.<\/span><\/p>\n [\/et_pb_tab][\/et_pb_tabs][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.5.3″ _module_preset=”default”][et_pb_column type=”4_4″ _builder_version=”4.5.3″ _module_preset=”default”][et_pb_text _builder_version=”4.5.3″ _module_preset=”default” header_2_font=”Arial||||||||”]<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”2_5,3_5″ _builder_version=”4.5.3″ _module_preset=”default”][et_pb_column type=”2_5″ _builder_version=”4.5.3″ _module_preset=”default”][et_pb_image src=”http:\/\/toxcel.com\/wp-content\/uploads\/2025\/06\/CLP-2025-white-paper-mockup.jpg” alt=”Mockup of Regulatory Services EU white paper” title_text=”Mockup of Regulatory Services EU white paper” _builder_version=”4.5.3″ _module_preset=”default” width=”80%” module_alignment=”center”][\/et_pb_image][et_pb_text _builder_version=”4.5.3″ _module_preset=”default” min_height=”40.8px” custom_margin=”8px|||0px|false|false” custom_padding=”0px|10px||10px|false|false”][\/et_pb_text][et_pb_blurb title=”We’d Love to Hear From You!” image=”http:\/\/toxcel.com\/wp-content\/uploads\/2025\/06\/Europe-from-space.jpg” alt=”Image of Europe from space” _builder_version=”4.5.3″ _module_preset=”default” header_font=”Arial|700|||||||” header_text_color=”#000000″ body_font=”Arial||||||||” body_text_align=”left” body_text_color=”#000000″ background_color=”rgba(132,169,197,0.5)” width=”80%” custom_margin=”|||42px|false|false” custom_padding=”15px|15px||15px|false|false”]Have a question or need more info? Fill out our contact form on the Contact Page<\/a><\/span><\/strong> and we\u2019ll get back to you soon![\/et_pb_blurb][\/et_pb_column][et_pb_column type=”3_5″ _builder_version=”4.5.3″ _module_preset=”default”][et_pb_text _builder_version=”4.5.3″ _module_preset=”default” text_font=”Arial||||||||” custom_margin=”8px||||false|false” custom_padding=”|10px||10px|false|false”]<\/p>\n The Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) in the UK and EU<\/b><\/a><\/span><\/p>\n The last of the REACH tonnage bands has passed \u2013 but there is still work to do! ECHA continue to evaluate dossiers and issue decisions on additional testing and further data requirements…<\/p>\n European Regulation\u00a0<\/b>on Classification, Labelling, and\u00a0<\/b>Packaging of Substances and Mixtures\u00a0<\/b>(CLP Regulation), EU Adoption of the\u00a0<\/b>Globally Harmonized System<\/b><\/a><\/span><\/p>\n To compile a compliant Safety Data Sheet (SDS) in the EU, two main regulations need to be taken into account:\u00a0Regulation (EC) No 1272\/2008 on Classification, Labelling and Packaging of Substances and\u00a0Mixtures (CLP Regulation)…<\/p>\nCLP<\/strong><\/h4>\n
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toXcel is available to help your company comply with the CLP Regulation for your chemicals and mixtures:<\/strong> \u200b<\/h5>\n
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Endocrine Disruptors in Europe <\/strong><\/h4>\n
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Health Canada and PMRA <\/span><\/span><\/strong><\/h4>\n
White Papers and Other Downloadable Resources<\/strong><\/h2>\n